Uzbekistan is one the countries which are allowed to participate in the annual American visa lottery program.
You must have Uzbekistan high school degree equivalent of a US secondary education or work experience according to the Instructions.
In the Official web site through the online application form when the form available for submission.. dvlottery.state.gov
Also take note Uzbekistan's 47.81% percent of entries which were illegitimate and therefore disqualified during selection process.
Embassy of the United States in Uzbekistan.
Pages for those people who had been selected as winners in the DV-2017 visa lottery program are here.
Any supporting documents that are in a language other than English must be accompanied by a complete English translation. The translator must include a sealed or stamped statement that the translation is accurate and that s/he is competent to translate.
Passport valid for travel abroad: Please note the name(s) and exit permit(s) of the child/children applying must be included in the parent's passport unless they possess own passport. Each applicant must provide the original passport and a photocopy of the front page with photo. For children, the applicant must make a photocopy of the passport page that shows the Exit Visa for Uzbek Citizens (former OVIR stamp) and the passport page that indicates the name of the child/children with their photo;
NOTICE FOR PEOPLE WHO SERVED IN THE THIRD COUNTRIES DURING THE MILITARY SERVICE! Ministry of Defense clearance certificate providing information regarding criminal records or convictions during the military service in a third country does not substitute a police certificate from that country.
Results of the standard medical examination: Applicants are required to undergo a medical examination by the Embassy panel physician.
The Medical Clinic will give the results of the medical examination to the applicant in a sealed envelope. Applicants must submit this sealed envelope with the results of the medical examination at the interview. The applicant must also present his/her vaccination records at the medical examination;
Diplomas from all educational institutions attended (for principal applicant only): an original AND photocopy;
Employment / work book (for principal applicant only): an original AND photocopy;
US$ 330 visa application fee for the primary applicant and each of his/her dependant family members.
Examples of DV scams used in Uzbekistan here.